On July 24, 2009, TV Guide Network announced that it had acquired the exclusive cable rights to the show and would air the fourth-season episodes two weeks after its ABC run with an option to strip the show daily, with plans to air it weekly starting in the fall of 2010.although there was talk of moving Lost to that same timeslot.The season finale is the episode called "East Side Story." On March 21, 2007, ABC renewed the series for a second season.In November 2007, the cast of the series made headlines when they threw their support behind the 2007 Writers' Strike by joining them on the picket line in solidarity.The departure of Pennette and Hayman added to the constant off-camera turnovers on the series, including the exiting or firing of five writers.These turn of events may have also contributed to Rebecca Romijn's decision to no longer be a full-time regular on the series in the third season, citing the move by new writers to make changes in the direction of several characters, especially Romijn's role as Alexis. As a result of the strike, creator Silvio Horta delayed plans for a musical episode and having Lindsay Lohan on board for a possible storyline until the third season.
Betty Suarez is a quirky, 22-year-old Mexican American woman from Queens, New York who is sorely lacking in fashion sense.
However, viewership dropped significantly in the show's third season, particularly in the important 18–49 age group.
In October 2009, the series was moved to Fridays, where it had trouble finding an audience.
Ferrera commented on the reason why they did this: "The issues coming up with the actors’ contracts are very similar to what the writers are dealing with right now, and we have to stay united and stand strong within the creative community for what we believe is fair." On November 25, the cast appeared in a 38-second video for "Speechless Hollywood" in which a black & white camera pulled away from a close up of Ferrera to showing her co-stars sitting next to her as they look directly at the camera without speaking.
Unfortunately on the day the renewal was announced, two of the show's executive producers, Marco Pennette and James Hayman, were let go.
The program's pilot was tested on several cable providers to gauge interest and feedback from viewers, most notably the Hispanic community, including those who are fans of the original Betty, who hoped that ABC would maintain the integrity of the original.