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From the Department of Internal Medicine, Division of Infectious and Immunologic Diseases, University of California Davis Medical Center, Sacramento, California (S. Data reporting the decreased effectiveness of metronidazole in the treatment of severe disease have been published.
The diagnosis of CDI should be based on a combination of clinical and laboratory findings.
A case definition for the usual presentation of CDI includes the following findings: (1) the presence of diarrhea, defined as passage of 3 or more unformed stools in 24 or fewer consecutive hours or its toxins or colonoscopic or histopathologic findings demonstrating pseudomembranous colitis.
FOUO files and files containing personally identifiable information may be transferred using SAFE.For privacy information, recipients will be notified that the data they are about to download is protected by the Privacy Act and that the recipients are responsible for its protection in accordance with Do D guidelines and policies.With SAFE any form of files, including zip files, may be sent to anyone with a valid email address.In such cases, it is important to communicate to the laboratory the necessity to do a toxin assay or culture for The vast majority of anaerobic infections arise from endogenous sources.However, a number of important clostridial infections and intoxications are caused by organisms acquired from exogenous sources. Veterans Affairs Hospital, and Infectious Disease Division, Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois (D. P.); and the Department of Microbiology, Leeds Teaching Hospitals National Health Service Trust and Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom (M. has been identified and has been responsible for more‐severe cases of disease worldwide.